Why hyponatremia in hyperglycemia

To view Dr. Hillier's publications, visit PubMed. This is an unprecedented time. It is the dedication of healthcare workers that will lead us through this crisis. Thank you for everything you do. Calc Function Calcs that help predict probability of a disease Diagnosis. Subcategory of 'Diagnosis' designed to be very sensitive Rule Out.

Disease is diagnosed: prognosticate to guide treatment Prognosis. Numerical inputs and outputs Formula. Med treatment and more Treatment. Suggested protocols Algorithm. Hyponatremia in the context of hypergylcemia is a commonly discussed problem. Remember hyponatremia is always a problem with free water. A common finding described on computed tomography CT imaging. A disease with a peribronchovascular distribution…. Though often used synonymously; Trapped Lung and Lung Entrapment technically describe separate entities along the….

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Abstract Background: Abnormal serum sodium levels in various diseases increase mortality; however, hyperglycemia depresses serum sodium concentration significantly. Results: A total of patients with severe hyperglycemia were enrolled, and the day mortality was Conclusion: Among patients with severe hyperglycemia, corrected sodium level is a better indicator of clinical outcomes compared with measured sodium levels, especially in this population with measured hyponatremia.

Keywords: Corrected sodium levels, Hyperglycemia, Mortality. Grouping according to measured or corrected sodium levels The sodium level was corrected according to the glucose level, with a correction factor of a 2. Study outcomes The primary outcome for this analysis was all-cause day mortality.

Table 1 Baseline characteristics of patients according to corrected sodium levels. Open in a separate window. Primary outcomes Among the patients with severe hyperglycemia, the day mortality was Table 2 Hazard ratios for day mortality according to the measured sodium level.

Table 3 Hazard ratios for day mortality according to the corrected sodium level. Footnotes Conflicts of interest: The authors declare that they have no conflicts of interest related to the subject matter or materials discussed in this article. References 1. Incidence and prevalence of hyponatremia.

Am J Med ; 7 Suppl 1 S30—5. N Engl J Med ; —9. Hyponatremia: evaluating the correction factor for hyperglycemia. Am J Med ; — Diabetes mellitus and electrolyte disorders. World J Clin Cases ; 2 — Hyponatremia and mortality risk: a Danish cohort study of acutely hospitalized patients. Eur J Endocrinol ; — Impact of hospital-associated hyponatremia on selected outcomes. Arch Intern Med ; — Hepatology ; 44 — Eur Heart J ; 28 —8. Associations of dysnatremias with mortality in chronic kidney disease.

Nephrol Dial Transplant ; 32 — Hyponatremia and mortality among patients on the liver-transplant waiting list. N Engl J Med ; — Hyponatremia is an independent predictor of in-hospital mortality in spontaneous intracerebral hemorrhage. Stroke ; 45 — Short-term case fatality rate and associated factors among inpatients with diabetic ketoacidosis and hyperglycemic hyperosmolar state: a hospital-based analysis over a year period.

Intern Med ; 49 — Predictors of hyperglycaemic crises and their associated mortality in Jamaica. Diabetes Res Clin Pract ; 73 — Prognostic factors of mortality among patients with severe hyperglycemia. Learn more. Hillier TA, et al. Hyponatremia: evaluating the correction factor for hyperglycemia.

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