Where is parasite found
These studies have found that this antigen-detection test is sensitive and specific for the detection of E. In a study in Bangladesh, E. In a study in Nicaragua among patients with diarrhoea, where E. In a study conducted in a cohort of Bangladeshi children found that the prevalence of E. No studies that have been carried till date using E. In addition to the antigen-detection test, several PCR-based tests specific for E. Rapid diagnostic test for the detection of E. Diagnosis of giardiasis is best accomplished by detection of Giardia antigen in stool, since the classic microscopic examination is less sensitive and specific.
A recent comparison of nine different antigen-detection tests demonstrated that all had high sensitivity and specificity, except one Giardia -specific antigen-detection tests are now also commercially available from several diagnostic companies, and their performance is quite good, except a few.
In addition to antigen-detection tests, PCR-based test for the detection of G. The population genetics of Giardia are complex. However, a recent genetic linkage study has confirmed the distinct grouping of Giardia in two major types Differentiation of these two assemblages of G.
Findings of the largest case-control study conducted to date on the relationship between genotypes of G. This study has shown that the Giardia assemblage A infection is associated with diarrhoea. In contrast, Giardia assemblage B infection is significantly associated with asymptomatic Giardia -associated infection, which was found to occur at a significantly higher rate The PCR-based approach allowed resolution of infection to the genotype level and brought some clarity to the findings of asymptomatic giardiasis.
Diagnosis of cryptosporidiosis is also best accomplished by detection of Cryptosporidium spp. Cryptosporidium spp. There are two main species of Cryptosporidium that infect humans: C. The PCR-based test is required for differentiation of these two species of Cryptosporidium spp. Both C. There are a few other species of Cryptosporidium that also can be found in humans 31 — Rapid diagnostic tests for the detection of G. Multiplex PCR-based test for the detection of E.
Personal communication, These modern antigen-detection tests and PCR-based tests need to be used for understanding the actual prevalence and epidemiology of these protozoan parasites.
Soil-transmitted helminth infections are invariably more prevalent in the poorest sections of the populations in endemic areas of developing countries.
The goal is to reduce morbidity from soil-transmitted helminth infections to such levels that these infections are no longer of public-health importance. An additional goal is to improve the developmental, functional and intellectual capacity of affected children Highly-effective, safe single-dose drugs, such as albendazole, now available, can be dispensed through healthcare services, school health programmes, and community interventions directed at vulnerable groups As these infections are endemic in poor communities, more permanent control will only be feasible where chemotherapy is supplemented by improved water supplies and sanitation, strengthened by sanitation education.
In the long term, this type of permanent transmission control will only be possible with improved living conditions through economic development.
Intestinal protozoa multiply rapidly in their hosts, and as there is a lack of effective vaccines, chemotherapy has been the only practised way to treat individuals and reduce transmission.
The current treatment modalities for intestinal protozoan parasites include metronidazole, iodoquinol, diloxanide furoate, paromomycin, chloroquine, and trimethoprim-sulphamethoxazole Nitazoxanide, a broad-spectrum anti-parasitic agent, was reported to be better than placebo for the treatment of cryptosporidiosis in a double-blind study performed in Mexico Genomes of these three important protozoan parasites have already been published 41 — 43 , and studies are underway to understand protective immunity to these protozoan parasites to develop vaccines for them.
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Savioli L, Albonico M. Soil-transmitted helminthiasis. Nat Rev Microbiol. Cappello M. We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Parasites are organisms that live in and feed off a living host. There are a variety of parasitic worms that can take up residence in humans.
Among them are flatworms, thorny-headed worms, and roundworms. The risk of parasitic infection is higher in rural or developing regions. The risk is great in places where food and drinking water may be contaminated and sanitation is poor.
When it comes to parasitic infection, flatworms and roundworms are likely culprits. These two types of parasitic worms can be found in a variety of habitats.
You can get a tapeworm , which is a type of flatworm, by drinking water contaminated with tapeworm eggs or larvae. Raw or undercooked meat is another way tapeworms can find their way into people. Tapeworms embed their heads into the intestinal wall and remain there. From there, certain types of tapeworms can produce eggs that mature into larvae that migrate to other parts of the body. A tapeworm looks like a long, white ribbon. They can grow up to 80 feet long and live in a human for up to 30 years.
Flukes are a type of flatworm. People are less likely than animals to contract flukes. Raw watercress and other freshwater plants are the main sources of flukes in humans. You can also get them when you drink contaminated water.
They make their home in your intestines, blood, or tissues. There are many varieties of flukes. None reach more than a few inches in length. Hookworms are transmitted through feces and contaminated soil. The most common way to make contact with this type of roundworm is to walk barefoot on soil infested with hookworm larvae.
They can pierce through the skin. Pinworms are tiny, fairly harmless worms. These roundworms, when fully matured, live in the colon and rectum. The female lays eggs around the anus, usually during the night.
The eggs can survive on bedding, clothing, and other materials. People contract them when they touch the eggs and end up putting them in their mouths.
They are able to multiply in humans, which contributes to their survival and also permits serious infections to develop from just a single organism. Protozoa that live in the blood or tissue of humans are transmitted to other humans by an arthropod vector for example, through the bite of a mosquito or sand fly.
The protozoa that are infectious to humans can be classified into four groups based on their mode of movement:. Helminths are large, multicellular organisms that are generally visible to the naked eye in their adult stages. Like protozoa, helminths can be either free-living or parasitic in nature. In their adult form, helminths cannot multiply in humans.
There are three main groups of helminths derived from the Greek word for worms that are human parasites:. Although the term ectoparasites can broadly include blood-sucking arthropods such as mosquitoes because they are dependent on a blood meal from a human host for their survival , this term is generally used more narrowly to refer to organisms such as ticks, fleas, lice, and mites that attach or burrow into the skin and remain there for relatively long periods of time e.
Arthropods are important in causing diseases in their own right, but are even more important as vectors, or transmitters, of many different pathogens that in turn cause tremendous morbidity and mortality from the diseases they cause. Parasitic infections cause a tremendous burden of disease in both the tropics and subtropics as well as in more temperate climates.
Of all parasitic diseases, malaria causes the most deaths globally. Malaria kills more than , people each year, most of them young children in sub-Saharan Africa. The Neglected Tropical Diseases NTDs , which have suffered from a lack of attention by the public health community, include parasitic diseases such as lymphatic filariasis , onchocerciasis , and Guinea worm disease.
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