Who is the manufacturer of enbrel

These patients should be carefully monitored. Rare cases of pancytopenia, including aplastic anemia, some fatal, have been reported. Exercise caution when considering ENBREL in patients who have a previous history of significant hematologic abnormalities.

Advise patients to seek immediate medical attention if they develop signs or symptoms of blood dyscrasias or infection.

Most reports occurred in patients also taking immunosuppressive agents, which may contribute to hepatitis B reactivation. If an anaphylactic reaction or other serious allergic reaction occurs, administration of ENBREL should be discontinued immediately and appropriate therapy initiated. The use of ENBREL in patients with granulomatosis with polyangiitis receiving immunosuppressive agents eg, cyclophosphamide is not recommended.

Based on a study of patients treated for alcoholic hepatitis, exercise caution when using ENBREL in patients with moderate to severe alcoholic hepatitis. The most commonly reported adverse reactions in RA clinical trials were injection site reaction and infection.

In clinical trials of all other adult indications, adverse reactions were similar to those reported in RA clinical trials. In general, the adverse reactions in pediatric patients were similar in frequency and type as those seen in adult patients. The types of infections reported in pediatric patients were generally mild and consistent with those commonly seen in the general pediatric population.

The risk of serious infection may increase with concomitant use of abatacept therapy. Amgen is a global biotechnology company that discovers, develops, manufactures and markets important human therapeutics based on advances in cellular and molecular biology.

Wyeth Pharmaceuticals, a division of Wyeth, has leading products in the areas of women's health care, cardiovascular disease, central nervous system, inflammation, hemophilia, oncology and vaccines. Wyeth is one of the world's largest research-driven pharmaceutical and health care products companies.

It is a leader in the discovery, development, manufacturing, and marketing of pharmaceuticals, vaccines, biotechnology products and non-prescription medicines that improve the quality of life for people worldwide.

This news release contains forward-looking statements that involve significant risks and uncertainties, including those discussed below and more fully described in the Securities and Exchange Commission reports filed by Amgen, including our most recent Form Q. Furthermore, Amgen's research, testing, pricing, marketing and other operations are subject to extensive regulation by domestic and foreign government regulatory authorities.

In addition, sales of Amgen's products are affected by reimbursement policies imposed by third party payors, including governments, private insurance plans and managed care providers. These government regulations and reimbursement policies may affect the development, usage and pricing of products.

In addition, while Amgen routinely obtains patents for its products and technology, the protection offered by patents and patent applications may be challenged, invalidated or circumvented by competitors.

Because forward-looking statements involve risks and uncertainties, actual results may differ materially from current results expected by Amgen. Amgen is providing this information as of December 23, , and expressly disclaims any duty to update information contained in this press release.

Amgen is not responsible for and does not endorse or control the content contained on this third-party website. Choose Your Condition. Ankylosing Spondylitis. Before starting ENBREL, tell your healthcare provider if you: Have any existing medical conditions Are taking any medicines, including herbals Think you have, are being treated for, have signs of, or are prone to infection.

You should not start taking ENBREL if you have any kind of infection, unless your healthcare provider says it is okay Have any open cuts or sores Have diabetes, HIV, or a weak immune system Have TB or have been in close contact with someone who has had TB Were born in, lived in, or traveled to countries where there is more risk for getting TB.

Ask your healthcare provider if you are not sure Live, have lived in, or traveled to certain parts of the country such as, the Ohio and Mississippi River valleys, or the Southwest where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis.

Are allergic to rubber or latex Are pregnant, planning to become pregnant, or breastfeeding Have been around someone with chicken pox. Moderate to Severe Rheumatoid Arthritis RA ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. Psoriatic Arthritis ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis.

Moderate to Severe Plaque Psoriasis ENBREL is indicated for chronic moderate to severe plaque psoriasis PsO in children 4 years and older and adults who may benefit from taking injections or pills systemic therapy or phototherapy ultraviolet light.

References: 1. Data on file, Amgen; [Summary of Clinical Efficacy; ]. Alexander ST, et al.